Abstract The necessity of recognizing Shia inheritance is obvious to everyone. Many of the famous savants and scientists have been grown along the time in Fars and Shiraz, the third shrine of Ahl-e-Bayt. Specifying the position of famous people in Shia interpretation would clear the civilizing role of Shia along the history in this area. Researching the period with the length of about 15 centuries, and discovering more than one hundred ten interpreters and their works in Fars interpretation school, we got to know Dashtaki dynasty. Many of the savants and scientists were interested in valuable works of this family. The goal of this writing is to explain the role and position of Dashtaki dynasty in Shia interpretation and to introduce their interpretative works based on library-researching and descriptive methods and with a network point of view. We found that Dashtaki dynasty was the most active dynasty in Fars interpretation school area with the most interpreters and interpretative works. In their interpretative works, sura and verse monographs and also the art of Ta’ligh and correction and some manuscripts are really eye-catching. Their tendency to philosophy and mysticism has never made them neglect other areas of Holy Book like moral, literal and scientific interpretations. They have used some other references besides the verses and narratives.