Before the advent of Islam, inscriptions were generally written in the heart of the mountains and on large stone beds, and mostly recorded and recorded historical events, actions and honors of kings and rulers, but after Islam, inscriptions on buildings They were hired and their situation changed. The use of inscriptions in Islamic architecture has been a sign of the religious beliefs of artists of each period. Khan School is located in Shiraz as a very important building left over from the Safavid period. What makes this school more famous than other schools in the city is its architecture and especially its beautiful inscriptions. Although this school has suffered a lot of destruction and restoration in different periods from Safavid times and many of the main tiles of the building have been destroyed, but the restored inscriptions are also unique in their kind. The purpose of this article is to review the inscriptions of Khan School in terms of subject and content, which have been less studied in other sources, and the research method has been based on library and field visits. The results of this research show that the subject of the inscriptions of this school, in addition to Quranic verses, includes prayers, hadiths and the names of old and new scribes, which have not been worked on in any of the previous researches.