The 1979 Islamic Revolution has been considered one of the most glorious revolutions in the world. According to historians, the protest movements leading to this revolution have been ongoing in different directions in different cities of Iran during the period from 1962 to 1975. The city of Shiraz, as one of the leading cities in the Islamic Revolution, has witnessed popular protests. On the other hand, the holy shrine of Ahmadbn Musa al-Akasham Shahkhraq (as) is recognized as an important religious and identity element in the Iranian-Islamic culture not only in Shiraz, but also in Iran and other Islamic countries, as the influence of this place Holy in different events, especially historical-political events of contemporary Iran can not be denied. Our question in this research is that the role of the holy holy shrine of Ahmad bin Moses al-Akashim Shahkhraq (as) in the protest movements leading to the Islamic Revolution of Iran from 1963 to 1962? To this end, we have sought to answer this question by using historical documents, books and articles, and in order to enrich the work, and in view of the lack of resources in some cases, we have interviewed influential people in the events. As a result, this shrine, in awareness, gathering and setting up protests, led to the collapse of the Imperial regime, and the Islamic Revolution's success has been effective, and the people of Shiraz, the holy shrine of Ahmad Ibn Musa (AS), are a safe haven and a base People-religious scholars have focused on the political movements with a focus on scholars and have a prominent place for targeted speeches and coordination and planning against the Imperial regime. In the form of this holy shrine as the most important center of gatherings and protests of the people of Shiraz in the protests leading to the Islamic Revolution of Iran, has been remembered. This research is descriptive-analytical and has been compiled in a library and interview format.