Obsessive-compulsive disorder, as its name suggests, is a specific disease whose obvious characteristic is obsessive or tempting. Religious obsession is related to the obsessive-compulsive practices, ordinances, etc., which are commonplace with many obsessive-compulsive disorder (OCD) and often known as the religious branch. Since Islamic teachings have comprehensive preventive and therapeutic directions in dealing with religious obsession. The present article seeks to provide the reader with a descriptive and analytical method, a clear cognition of the role of the great clergy; in the treatment (removal) of this type of obsession using the valuable teachings and whether it is curable. According to the research findings of a person with this type of obsession, using religion and using religious scholarship advice can overcome his problem and get rid of obsession. But if this religious obsession is rooted in spirit and soul and is not fully curable with religious and religious advice, with an interactive therapeutic and therapeutic treatment and a religious adviser (psychiatrist) with medication (psychotherapy) Physician) and psychotherapy (clinical psychologist) can be cured. Based on the findings of the research, it can be concluded that the role of the Supreme Shiite clergy in the treatment of obsessive-compulsive disorder is very important and necessary, and this kind of obsession is completely curable.