The purpose of presenting this research is to learn about the proud life of Ayatollah Sheikh Abdul Karim Haeri Yazdi, the founder of Qom Seminary. This research has been done in a review form and with the method of document and library study. Ayatollah Sheikh Abdul Karim Haeri is one of the prominent and distinguished scholars and clerics who has played a worthy role in the contemporary history of Iran, the establishment of Qom seminary and even the history of Shiism. This great Shiite scholar has spent 16 years of his blessed life in Arak city. Grand Ayatollah Sheikh Abdul Karim Haeri Mehrjardi is a descendant of Shia scholars, whose eternal legacy is Qom Seminary. In front of the professors of jurisprudence and principles, such as the late Sheikh Ansari and Akhund Khorasani, he has a solid and independent basis that can be included in the ranks of the geniuses and scholars of Islam, and beyond the scientific personality in piety, asceticism, holiness, piety, communication and recourse. To the family of Revelation and Prophethood, and especially to His Highness Hazrat Baqiyatullah, it was a rare moment, and in recent centuries, few people have reached his rank.